As humanity prepares for longer space missions, including future journeys to the Moon and Mars, scientists are discovering that spaceflight may affect the human body in ways that are still poorly understood. Now, researchers have identified a potential new concern for women: changes in the vaginal microbiome caused by the physical and psychological stresses of space travel. In a first-of-its-kind study, researchers led by Begum Mathyk, MD , a physician-scientist in the Department of Obstetrics and Gynecology at the USF Health Morsani College of Medicine, investigated how altered gravity and spaceflight-related stress affect the vaginal microbiome. Published in Frontiers in Microbiology , the study found that parabolic flight can produce short-term physiological stress and cause measurable changes in the vaginal microbiome. Interestingly, the effects were much stronger in the vaginal microbiome than in the oral microbiome. The findings could become increasingly important as space agenci...